The cellular stress response increases measles virus-induced cytopathic effect.

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Buthionine Sulfoximine Inhibits Cytopathic Effects and Apoptosis Induced by Infection with AIK-HDC Strain of Measles Virus

Measles virus (MV) is a highly contagious agent which causes a major health problem in developing countries. We studied the effect of buthionine sulfoximine (BSO) on the replication of an AIK-HDC strain of MV and its induced apoptosis in Vero cell lines. Methods: In this study, toxicity of BSO on Vero cells was investigated first, resulted in determination of sub-lethal or non-toxic concentrati...

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Constitutive overexpression of the major inducible 70 kDa heat shock protein mediates large plaque formation by measles virus.

Induction of the cellular stress response elevates cytoplasmic levels of heat shock proteins (HSPs) belonging to multiple families. When infected with canine distemper virus or measles virus (MV), cells containing elevated HSPs support increased viral gene expression and cytopathic effect. The present work tests the hypothesis that increases in the major inducible 70 kDa HSP (hsp72) are suffici...

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Buthionine sulfoximine inhibits cytopathic effects and apoptosis induced by infection with AIK-HDC strain of measles virus.

BACKGROUND Measles virus (MV) is a highly contagious agent which causes a major health problem in developing countries. We studied the effect of buthionine sulfoximine (BSO) on the replication of an AIK-HDC strain of MV and its induced apoptosis in Vero cell lines. METHODS In this study, toxicity of BSO on Vero cells was investigated first, resulted in determination of sub-lethal or non-toxic...

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buthionine sulfoximine inhibits cytopathic effects and apoptosis induced by infection with aik-hdc strain of measles virus

measles virus (mv) is a highly contagious agent which causes a major health problem in developing countries. we studied the effect of buthionine sulfoximine (bso) on the replication of an aik-hdc strain of mv and its induced apoptosis in vero cell lines. methods: in this study, toxicity of bso on vero cells was investigated first, resulted in determination of sub-lethal or non-toxic concentrati...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 1998

ISSN: 0022-1317,1465-2099

DOI: 10.1099/0022-1317-79-7-1769